MXE is usually snorted, swallowed or injected. In small doses the following effects may occur and may last for up to 7 hours: euphoria empathy pleasant sensory experience dissociation vivid hallucinations introspection anti-depressant 2, 3, 5 Some adverse effects include: disorientation confusion dizziness anxiety rapid heart rate nausea paranoia vomiting slurring or difficulty speaking psychomotor agitation e.
Injecting drugs, including MXE, can cause damage to veins and other tissues. Dependence and tolerance There is limited evidence regarding MXE and dependence, however, experts believe that the similarity to ketamine means that it carries a comparable risk of dependence. Path2Help Not sure what you are looking for? Find out more. Ketamine: 50 Years of Modulating the Mind. Frontiers in Human Neuroscience.
Psychonaut Wiki. Methoxetamine World Health Organization. Bright S. Not for human consumption: new and emerging drugs in Australia. Melbourne Alcohol and Drug Foundation Hartney E. Methoxetamine n. Morgan C, Noronha, L. It was claimed by people selling the drug that methoxetamine is an alternative to ketamine without the risks to the bladder that ketamine has, but there is no evidence for this whatsoever, in fact it appears to damage the bladders of mice.
Addicted ketamine users suffer cravings that disrupt their lives and the drugs can cause negative effects on memory. Regular users can regularly feel a bit befuddled. These mental effects seem to reverse when users quit the drug. Because so little is known about it, there is an argument that taking methoxetamine is always unacceptably risky. Even so, if you do use the drug, there are ways of reducing the chances of getting harmed. Digital scales which measure at the 0. If you add to your dose at this point, the combined effects may be stronger than anticipated.
It is likely that, like ketamine, tolerance builds up rapidly, so a regular user needs more and more to get the effects they want.
The more you use, the higher your risk of suffering cravings and symptoms if you try to stop, and so becoming addicted. If your tolerance is increasing, be especially mindful of the risks of addiction. Drug Science is an independent, science-led drugs charity. We rely on donations to continue to promote evidence-based information about drugs without political or commercial interference.
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Name Email address I would like to receive: Latest news and developments Events Volunteer Opportunities By checking this box I consent to the use of my information provided for email marketing purposes. Home Methoxetamine. What is methoxetamine? Are there different types of methoxetamine and how do they compare?
How does methoxetamine work as a drug in the brain and body? Does methoxetamine have medical uses? What effects does methoxetamine have when someone takes it? What are the risks of using methoxetamine? Can they be avoided or reduced? Are some people at higher risk? Is it riskier to use methoxetamine with other drugs in your system?
How addictive is methoxetamine? What are the harms of using methoxetamine long-term? Also Known As: Methoxetamine is also known as MXE, m-ket sometimes written as m ket , k max, k-maxx, kmaxx , mexxy sometimes written as mexy, mexxi , mexxiem, mkat, mxxe, methoxatamine, methoxetimine, and methoxetamin.
Drug Class: MXE is an arylcyclohexylamine. It's classified as a dissociative hallucinogen. Common Side Effects: MXE can cause increased energy, euphoria, auditory and visual hallucinations, disassociation m-hole , severe ataxia, nystagmus.
MXE is typically produced in the form of a white or off-white powder and may be labeled "not intended for human consumption" or sold as a "research chemical. There are several ways that people take MXE. Some take it orally or sublingually under the tongue. Some take it by nasal insufflation or snorting it into the nose. It can also be inserted into the rectum, where it's absorbed into the bloodstream, or injected into a muscle.
Doses typically range from 5 mg to 90 mg. If the drug is snorted, it can take 30 to 90 minutes to feel the effect, which can lead people to "top-up" or take more before the drug kicks in. This is a dangerous practice because the drug can build up in your system and lead to synergistic adverse effects.
The effects usually last for one to three hours. If MXE is injected, the effects can begin within five minutes and last for as little as one hour. Like other psychoactive drugs , the MXE high is described as pleasurable and includes stimulant, relaxant, and dissociative effects.
But MXE also has unpredictable and intense side effects—particularly with higher doses—that are extremely unpleasant both physically and psychologically. MXE has been available on the Internet since through online chemical manufacturers and head shops who sell it as a "research chemical" and as a "legal high. The lack of credible research evidence on MXE makes it a risky substance to take both in the short term and the long term. In the short term, if you suffer from acute complications of the drug, the doctors who try to help you in the emergency room will likely not be well-versed in what you have taken or how to best treat it.
Information is not yet available on the long-term effects of MXE, so we don't currently know how taking MXE might affect your future mental or physical health, your fertility, or the health of your baby if you are pregnant or breastfeeding when you take it. New psychoactive substances or "legal highs" like MXE are not a safe, legal alternative to ketamine.
In fact, they're often more potent and unpredictable than the illicit drug they are designed to mimic. MXE has stimulant and dissociative effects, with the stimulant effects predominating at lower doses and the dissociative effects at higher doses. Depending on the set and setting and your personal reaction to the drug, you can experience an altered state of consciousness that can range from a dreamlike state to a terrifying bad trip experience of heightened, intense anxiety that can go on for several hours.
Lower Doses up to 20 mg : These feelings can continue as an "afterglow" for one to two hours after the main effects of the drug wear off.
Higher doses 40 mg to 50 mg : When taken in higher doses, the effects of MXE are much more intense and more similar to related drugs like ketamine and PCP , including:.
Marijuana appears to intensify MXE in a negative way, causing severe disorientation and distress, slurred speech, and difficulty communicating. People can also become hyperthermic and hyperpyrexic high fever , which is potentially fatal. Hospital reports show that, while people can recover from MXE toxicity, this recovery period can require several days of hospitalization, with treatment including detox medication, intravenous fluids, and respiratory support. In addition, news stories have blamed several deaths on the consumption of the drug.
Very little objective information is available about MXE—most of it is anecdotal, posted on internet forums by people who use it, or reported by emergency physicians who have dealt with acute cases. These individual reports give an idea of what someone says about their personal experience with the drug, but do not necessarily predict other people's experiences.
If you or anyone else has taken MXE and appear to be losing consciousness, call immediately. Inform the paramedic that MXE was taken, as well as any other drugs or alcohol that were also consumed. The effects of MXE can be life-threatening. If someone you care about is using MXE, you might notice the following signs:.
Anecdotal reports from people who use MXE indicate that tolerance builds up quickly and that the drug has a high potential for addiction.
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